The Genetic Profile of Alzheimer's Disease: Updates and Considerations
Inherited variants in the APP, PS1, PS2, and APOE genes all cause A-beta accumulation in the brain. Mutations in the PS1 gene are responsible for the most aggressive form of AD and account for 18 ...
Genes and Genetics
Genetics is the study of genes. Our genes carry information that gets passed from one generation to the next. For example, genes are why one child has blonde hair like their mother, while their ...
What causes young-onset dementia?
They usually start when a person is in their mid 30s. CADASIL is caused by a genetic mutation in the NOTCH3 gene. It is usually inherited from a parent who has a 50% chance of passing on the mutated ...
Understanding how tiny changes in several genes could contribute towards risk of Alzheimer’s disease
The causes of Alzheimer's disease are thought to be a complex mix of genetics, lifestyle and environmental factors. Variations in the gene ApoE are known to increase risk of Alzheimer's disease, but ...
Alzheimer’s and COVID-19 Share a Genetic Risk Factor
The researchers investigated four variants on the OAS1 gene, all of which dampen its expression (activity). They found that the variants increasing the risk of Alzheimer’s disease are linked ...
What Is Early Onset Familial Alzheimer Disease (eFAD)?
In a given family with an APP or presenilin-2 (but not presenilin-1) mutation, carriers who also have inherited an ApoE4 gene tend to get sick at a younger age than their relatives who have the more ...
Mutant Gene Stops At-Risk People From Getting Alzheimer's
But that story just became a little more complicated -- in a way that could potentially save the brains of millions who've inherited the APOE4 gene. An international research team led by Greicius ...
Genetics and Genomics
Welcome to the Genetics and Genomics free online conference! The event is now available on-demand and you can attend sessions including keynotes sessions by Dr. Michael Snyder, Dr. John Quackenbush, ...
Genetics and Genomics
The theme of this conference is a range of genetics and genomics topics such as Bioinformatics and Quantitative Genomics, Cancer Detection, Cancer Genomics, Clinical Genomics, Complex Diseases, ...
Drugs for Genetic Testing of s
Dabrafenib is used to treat melanoma with a specific BRAF V600E gene mutation ... which is associated with an inherited disease called as Huntington's disease. Tezacaftor and Ivacaftor tablets ...
Landmark Alzheimer's Prevention Trial Unable to Show Significantly Slower Cognitive Decline in Inherited Form of Disease
Groundbreaking Colombian study will still have major impact on Alzheimer's prevention research PHOENIX, June 16, 2022 /PRNewswire/ -- A precedent-setting prevention trial in Colombia has found ...
